Discovery
Getting antibodies into your hands quickly is important.
You may receive your first delivery as early as 8 weeks.
Providing you with a comprehensive data package allows you to make data driven decisions and focus on those leads that really matter.

To date, Adimab scientists have worked on over one hundred different targets and have successfully completed discovery programs on the following protein classes:

  • RTK-ECDs
  • Serum proteins
  • Enzymes
  • TNF superfamily receptors
  • Cell/ECM adhesion receptors
  • Natural Peptides
  • Cytokines
  • Ion channels
  • GPCRs

Adimab uses its libraries of fully human IgGs expressed in yeast to discover full length IgGs that meet the highest quality and developability standards.

The discovery process selects for:

  • Affinity
  • Expression
  • Species cross-reactivity, typically human, mouse and cyno
  • Epitopic diversity
  • Whole-cell binding
  • Thermal stability
  • Poly-specificity
  • In vivo half-life
  • Developability

As an Adimab partner, you can expect:

  • Cycle time of 4 weeks from antigen to assay
  • Delivery of fully characterized IgGs as early as 8 weeks
  • A complete data package including:
    • Affinity measurements
    • Molecular mass by mass spectrometry
    • DNA/Protein sequence
    • Sequence analysis including estimated pI
    • Epitopic binning
    • Poly-reactivity and specificity data
    • Melting temperature
    • Aggregation by Dynamic Light Scattering (DLS)
    • Size Exclusion Chromatography (SEC)
    • Cross Interaction Chromatography (CIC)
    • Other assays as required